Data represent an average and SD of 3 replicates. nucleotide exchange element (GEF), is definitely overexpressed in GB tumors and plays a role in advertising TWEAK-Fn14 mediated glioma invasion. Here, further investigation exposed an important part for SGEF in glioma cell survival. SGEF manifestation is definitely up-regulated by TWEAK-Fn14 signaling via NF-B activity while shRNA-mediated … Continue reading Data represent an average and SD of 3 replicates